Strictly for Laboratory Research Use Only. Not for human or veterinary use.
LPure99Research

Metabolic

CAS 910463-68-2

Semaglutide

Long-acting GLP-1 receptor agonist peptide.

COA · Batch SEM-260820-C Verified · AR-SE-M-260820-C-SEM
  • Third-Party Tested
  • High Purity >99%
  • Lyophilized Powder
  • COA Verified
SEMLYOPHILIZED · 2MGSEM-260820-CRESEARCH USE ONLY 3D render · placeholderSEM · 2mg

Analytical data

Batch SEM-260820-C

Sample S-SEM-260820-C-C · Tested Aug 27, 2026 · Independent ISO/IEC 17025 laboratory (placeholder)

Third-party verifiedReport AR-SE-M-260820-C-SEMVerify
02468101214161820050100Retention time (min)mAU (220 nm)11.80 min · 99.58%
PeakRT (min)Area (mAU·s)Area %ID
18.601550.08Impurity
210.203480.19Impurity
311.80183,22799.58Semaglutide
412.702700.15Impurity
Column
C18, 4.6 × 250 mm, 5 µm
Gradient
5 → 65% B over 20 min (A: 0.1% TFA in water; B: 0.1% TFA in acetonitrile)
Flow rate
1.0 mL/min
Detection
UV 220 nm

Mock analytical data for demonstration. Replace with the signed, batch-specific report issued by your testing laboratory.

Chemical specifications

Semaglutide at a glance

Lot SEM-260820-C
Chemical specifications for Semaglutide
Chemical NameSemaglutide (NN9535)
CAS #910463-68-2
Molecular FormulaC187H291N45O59
Molecular Weight4113.6 g/mol
SequenceH-Aib-EGTFTSDVSSYLEGQAAK(γE-2×OEG-C18 diacid)EFIAWLVRGRG-OH
Purity> 99% (HPLC) · this batch 99.58%
AppearanceWhite lyophilized powder

Placeholder specification data for this demo. Replace with your supplier and batch records before launch.

Overview

Semaglutide is a synthetic 31-amino-acid GLP-1 analogue with an Aib substitution at position 8 and a C18 fatty diacid attached via a spacer to lysine-26, conferring high albumin affinity and resistance to DPP-4 degradation. Supplied as a lyophilized powder for in-vitro research.

  • GLP-1 receptor agonist, 94% sequence homology to native GLP-1
  • C18 fatty diacid for albumin binding
  • HPLC purity ≥ 99% on every batch
  • Batch-specific Certificate of Analysis included

Manufacturing & characterization

01

Solid-phase synthesis

Produced by Fmoc solid-phase peptide synthesis followed by preparative RP-HPLC purification.

02

Characterized by LC-MS

Identity confirmed by electrospray mass spectrometry against the theoretical monoisotopic mass.

03

Lyophilized for stability

Freeze-dried under vacuum in sealed, nitrogen-flushed vials to preserve integrity in transit.

Molecular formula
C187H291N45O59
Molecular weight
4113.6 g/mol
CAS number
910463-68-2
Sequence
H-Aib-EGTFTSDVSSYLEGQAAK(γE-2×OEG-C18 diacid)EFIAWLVRGRG-OH
Purity (HPLC)
> 99%
Form
Lyophilized powder
Vial sizes
2 mg · 5 mg · 10 mg
Solubility
Bacteriostatic water, sterile water

Values are placeholder specifications for this demo and should be replaced with your supplier data.

Customer reviews

What researchers say about Semaglutide

5.0/ 5

5 reviews · 5 verified

  • 55
  • 40
  • 30
  • 20
  • 10

Verified purchase reviews are linked to a shipped order.

  • Matches the COA exactly

    Verified purchase

    Ran our own HPLC on arrival and the purity came back within 0.2% of the certificate. Lyophilized cake was intact and reconstituted cleanly.

    M. Okafor · Cell biology core, university lab · Sep 30, 2026 · 10mg vial

  • Consistent across three lots

    Verified purchase

    We have ordered the same peptide from three different batches and the mass spec identity has been spot-on every time. Cold packs were still frozen on delivery.

    J. Lindqvist · Contract research organisation · Sep 22, 2026 · 5mg vial

  • Clear documentation

    Verified purchase

    The batch-specific COA, HPLC trace and MS spectrum are exactly what our QA team needs for incoming inspection. Saves a lot of back-and-forth.

    S. Nakamura · Quality assurance, pharma · Sep 05, 2026 · 10mg vial

  • Reconstitutes with no particulates

    Verified purchase

    Dissolved in bacteriostatic water without any cloudiness. Nitrogen-flushed vial and a crisp lyophilized cake, as advertised.

    T. Brennan · Independent research lab · Aug 09, 2026 · 2mg vial

  • Exactly as specified

    Verified purchase

    Molecular weight confirmed on our Q-TOF to within 0.3 Da. Great value with the bulk tier discount.

    K. Adeyemi · Protein chemistry group · Jul 08, 2026 · 5mg vial

Sample reviews for demonstration only.

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