Strictly for Laboratory Research Use Only. Not for human or veterinary use.

Tissue Repair

CAS 77591-33-4

TB-500

Synthetic Thymosin Beta-4 peptide.

COA · Batch TB5-260815-B Verified · AR-TB-5-260815-B-TB5
  • Third-Party Tested
  • High Purity >99%
  • Lyophilized Powder
  • COA Verified
TB5LYOPHILIZED · 5MGTB5-260815-BRESEARCH USE ONLY 3D render · placeholderTB5 · 5mg

Analytical data

Batch TB5-260815-B

Sample S-TB5-260815-B-B · Tested Aug 22, 2026 · Independent ISO/IEC 17025 laboratory (placeholder)

Third-party verifiedReport AR-TB-5-260815-B-TB5Verify
02468101214161820050100Retention time (min)mAU (220 nm)10.30 min · 99.36%
PeakRT (min)Area (mAU·s)Area %ID
17.102360.13Impurity
28.705300.29Impurity
310.30182,82299.36TB-500
411.204120.22Impurity
Column
C18, 4.6 × 250 mm, 5 µm
Gradient
5 → 65% B over 20 min (A: 0.1% TFA in water; B: 0.1% TFA in acetonitrile)
Flow rate
1.0 mL/min
Detection
UV 220 nm

Mock analytical data for demonstration. Replace with the signed, batch-specific report issued by your testing laboratory.

Chemical specifications

TB-500 at a glance

Lot TB5-260815-B
Chemical specifications for TB-500
Chemical NameTB-500 (Thymosin β4 (synthetic), Tβ4)
CAS #77591-33-4
Molecular FormulaC212H350N56O78S
Molecular Weight4963.4 g/mol
SequenceAc-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH
Purity> 99% (HPLC) · this batch 99.36%
AppearanceWhite lyophilized powder

Placeholder specification data for this demo. Replace with your supplier and batch records before launch.

Overview

TB-500 is a synthetic version of the naturally occurring 43-amino-acid protein Thymosin Beta-4 (Tβ4), an actin-sequestering peptide found in nearly all mammalian cells. The N-terminus is acetylated as in the native protein. Supplied as a lyophilized powder for in-vitro research.

  • 43-amino-acid actin-sequestering peptide
  • N-terminal acetylation, as in native Tβ4
  • HPLC purity ≥ 99% on every batch
  • Batch-specific Certificate of Analysis included

Manufacturing & characterization

01

Solid-phase synthesis

Produced by Fmoc solid-phase peptide synthesis followed by preparative RP-HPLC purification.

02

Characterized by LC-MS

Identity confirmed by electrospray mass spectrometry against the theoretical monoisotopic mass.

03

Lyophilized for stability

Freeze-dried under vacuum in sealed, nitrogen-flushed vials to preserve integrity in transit.

Molecular formula
C212H350N56O78S
Molecular weight
4963.4 g/mol
CAS number
77591-33-4
Sequence
Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH
Purity (HPLC)
> 99%
Form
Lyophilized powder
Vial sizes
5 mg · 10 mg
Solubility
Water, bacteriostatic water, PBS

Values are placeholder specifications for this demo and should be replaced with your supplier data.

Customer reviews

What researchers say about TB-500

4.3/ 5

6 reviews · 5 verified

  • 53
  • 42
  • 31
  • 20
  • 10

Verified purchase reviews are linked to a shipped order.

  • Matches the COA exactly

    Verified purchase

    Ran our own HPLC on arrival and the purity came back within 0.2% of the certificate. Lyophilized cake was intact and reconstituted cleanly.

    M. Okafor · Cell biology core, university lab · Oct 01, 2026 · 10mg vial

  • Good product, slow courier

    Verified purchase

    Material itself is excellent and the batch documentation is thorough. Standard shipping took four days to reach us, which is at the top of the quoted window.

    R. Patel · Biotech start-up · Sep 14, 2026 · 5mg vial

  • Solid reference material

    Used as a reference standard for a receptor binding assay. Behaved as expected. Would appreciate a 1 mg size for method development.

    A. Fernández · Pharmacology department · Aug 23, 2026 · 10mg vial

  • Reconstitutes with no particulates

    Verified purchase

    Dissolved in bacteriostatic water without any cloudiness. Nitrogen-flushed vial and a crisp lyophilized cake, as advertised.

    T. Brennan · Independent research lab · Aug 10, 2026 · 10mg vial

  • Fine, but packaging could improve

    Verified purchase

    Peptide quality is good. The outer box arrived dented, though the insulated inner container and vials were unharmed.

    L. Moreau · Analytical services lab · Jul 27, 2026 · 5mg vial

  • Exactly as specified

    Verified purchase

    Molecular weight confirmed on our Q-TOF to within 0.3 Da. Great value with the bulk tier discount.

    K. Adeyemi · Protein chemistry group · Jul 09, 2026 · 5mg vial

Sample reviews for demonstration only.

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